α-ALKYLATION AND α-ARYLATION OF CARBONYL GROUPS: NICKEL-PHOSPHINE COMPLEX-CATALYZED GRIGNARD COUPLING OF <i>vic</i>-BROMOTRIMETHYLSILOXYALKENES

Abstract

Abstract In the presence of [Ni(dppp)Cl2] as a catalyst, vic-bromotrimethylsiloxyalkenes (1)couple with Grignard reagents to produce alkylated and arylated silyl enol ethers, or, after acid hydrolysis, the corresponding α-alkylated and α-arylated carbonyl compounds. In these reactions, 1 can be regarded as an enolonium equivalent.