Concepedia

Cystathionine γ-Lyase Deficiency Protects Mice from Galactosamine/Lipopolysaccharide-Induced Acute Liver Failure

Kazuhiro Shirozu, Kentaro Tokuda, Eizo Marutani, David J. Lefer, Rui Wang, Fumito Ichinose

Antioxidants and Redox Signaling · 2013 · 90 citations · 29 references

DOIFull text

Open access

Abstract

Congenital deficiency or chemical inhibition of CSE increases thiosulfate levels in the liver and prevents ALF at least in part by augmentation of antioxidant and anti-apoptotic mechanisms.

References

29

H <sub>2</sub> S as a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine γ-Lyase

Guangdong Yang, Lingyun Wu, Bo Jiang et al. · Science · 2008 · 2.3K citations · Full text

Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1.

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, , +13

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, , +6

Galactosamine-induced sensitization to the lethal effects of endotoxin.

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, , +17

Nrf2 Protein Up-regulates Antiapoptotic Protein Bcl-2 and Prevents Cellular Apoptosis

Suryakant Niture, Anil K. Jaiswal · Journal of Biological Chemistry · 2012 · 530 citations · Full text