New England Journal of Medicine · 1966 · 342 citations · 21 references
Veterinary MedicineImmunologyInfectious DiseasesImmunology Of Infectious DiseasesRhinologyVirologyNasal ObstructionRespiratory Infectious DiseasesViral DiagnosticsViral InfectionsCommon ColdNasal SymptomsNeutralizing Antibody ResponsesRhinovirus InfectionViral Rhinitis
RHINOVIRUSES have been associated with 10 to 30 per cent of acute upper respiratory illnesses in several groups of adults.1 2 3 4 5 6 In March, 1963, a study was undertaken to define the etiology and epidemiology of acute respiratory disease in a population of working adults, and the role of a number of viruses was studied initially. Coincident with the beginning of the investigation, improvements in technology occurred that facilitated the isolation of rhinoviruses and shifted emphasis to these agents. During the first three years of the study, the period considered in this report, approximately a quarter of the acute respiratory illnesses were . . .
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