Pyrimidines. XV. (Amino Acids. II.) <scp>DL</scp>‐β‐(dihydroxypyrimidinyl) alanines

Abstract

Abstract The Prepration of two uracil derivatives of alanine, DL ‐β‐(5‐uracilyl)alanine and DL ‐β(6‐uracilyl)alanine, are reported. A structural analog, dl‐4,6‐dihydroxy‐β‐(2‐(pyrimidinyl)alanine, which was reported to be labile to acid hydrolysis, has now been successfully prepared in our laboratories. The relationship between the relative position of an alanine moity on some nitrogen hetrocyclic ring systems and their color formation with ninhydrin are discussed.