Genetic variation in the GSTM3 promoter confer risk and prognosis of renal cell carcinoma by reducing gene expression - Concepedia

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Genetic variation in the GSTM3 promoter confer risk and prognosis of renal cell carcinoma by reducing gene expression

DOI Full Paper Access

24

Citations

33

References

2013

Year

Xiaojun Tan, Ying Wang, Yi Han, WEI-JUNG CHANG, Tong Su, Jian Hou, Da Xu, Yang Yu, Wenli Ma, Timothy C. Thompson,

British Journal of Cancer

Abstract

Glutathione S-transferase mu 3 may function as a tumour suppressor in RCC. rs1332018 genetic variants predispose the host to downregulating GSTM3 expression in kidney, facilitate carcinogenesis, and predict an unfavourable postoperative prognosis of RCC.

References

	Year	Citations

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