Spinal Stenosis Caused by Epidural Lipomatosis in Cushing's Syndrome

Abstract

CENTRIPETAL fat deposition is a well known clinical feature of excessive endogenous or exogenous adrenal glucocorticoids. We describe an unusual case of central spinal stenosis caused by excessive epidural fat in a patient with Cushing's syndrome secondary to prolonged therapy with high doses of glucocorticoids. Only one other case report of this phenomenon could be located in the medical literature.1 Case ReportA 53-year-old woman with Graves' disease, euthyroid after radioiodine therapy, had infiltrative ophthalmopathy with optic-nerve involvement. When she was treated with prednisone, 150 mg per day, cushingoid features developed rapidly. Two months after the initiation of therapy, with . . .