Evidence that imipramine activates 5-HT1C receptor function

Behavioral despair in mice: a primary screening test for antidepressants.

Porsolt Rd, Aurélie Bertin, M Jalfre · PubMed · 1977 · 3.3K citations

Medicine, Pharmacology, Psychiatry +17

8-Hydroxy-2-(di-n-propylamino)-tetralin discriminates between subtypes of the 5-HT1 recognition site

Derek N. Middlemiss, John R. Fozard · European Journal of Pharmacology · 1983 · 869 citations

Life Sciences, Neuroscience, Molecular Neuroscience +6

Receptor binding profile of R 41 468, A novel antagonist at 5-HT2 receptors

J.E. Leysen, F. Awouters, Ludo Kennis et al. · Life Sciences · 1981 · 846 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Molecular pharmacology of 5-HT1 and 5-HT2 recognition sites in rat and pig brain membranes: Radioligand binding studies with [3H]5-HT, [3H]8-OH-DPAT, (−)[125I]iodocyanopindolol, [3H]mesulergine and [3H]Ketanserin

Daniël Hoyer, G. Engel, Hans O. Kalkman · European Journal of Pharmacology · 1985 · 577 citations

Life Sciences, Neuroscience, Pharmacology +13

Characterization of the binding of 3H-SCH 23390, a selective D-1 receptor antagonist ligand, in rat striatum

William Billard, Vilma Ruperto, Gordon Crosby et al. · Life Sciences · 1984 · 567 citations · Full text

Medicine, Neuroscience, Pharmacology +16