The influence of medium composition and matrix on long-term cultivation of primary porcine and human hepatocytes

Hepatocyte function and extracellular matrix geometry: long‐term culture in a sandwich configuration

James Dunn, Martin L. Yarmush, H.G. Koebe et al. · The FASEB Journal · 1989 · 737 citations

Life Sciences, Bioengineering, Physiology +16

A simple, versatile, nondisruptive method for the isolation of morphologically and chemically pure basement membranes from several tissues

Elias Meezan, J. Thomas Hjelle, Klaus Brendel et al. · Life Sciences · 1975 · 340 citations

Engineering, Biochemistry, Cell Biology +9

Stable immobilization of rat hepatocyte spheroids on galactosylated nanofiber scaffold

Kian Ngiap Chua, Wei-Seng Lim, Pengchi Zhang et al. · Biomaterials · 2004 · 259 citations

Engineering, Bioengineering, Biomedical Engineering +16

In vitro evaluation of a novel bioreactor based on an integral oxygenator and a spirally wound nonwoven polyester matrix for hepatocyte culture as small aggregates

Leonard M. Flendrig, J.W. La Soe, George G.A. Jörning et al. · Journal of Hepatology · 1997 · 250 citations · Full text

Engineering, Bioengineering, Biomedical Engineering +17

Drug metabolism in hepatocyte sandwich cultures of rats and humans

A. D. Kern, A. Bader, R. Pichlmayr et al. · Biochemical Pharmacology · 1997 · 187 citations

Medicine, Biochemistry, Pharmacology +12