Epimorphin promotes human hepatocellular carcinoma invasion and metastasis through activation of focal adhesion kinase/extracellular signal-regulated kinase/matrix metalloproteinase-9 axis - Concepedia

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Epimorphin promotes human hepatocellular carcinoma invasion and metastasis through activation of focal adhesion kinase/extracellular signal-regulated kinase/matrix metalloproteinase-9 axis

85

Citations

24

References

2011

Year

Lei Shi, Junnian Zhou, Chunjiang Fu, Lin Chen, Hongfeng Yuan, Yunfang Wang, Xinlong Yan, Yingchen Xu, Quan Zeng, Wen Yue,

Abstract

Our results show that EPM, secreted by activated HSCs within HCC stroma, promotes invasion and metastasis of cancer cells by activating MMP-9 expression through the FAK-ERK pathway.

References

	Year	Citations

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