Intra‐articular injection of hyaluronic acid for the reduction in joint adhesion formation in a rabbit model of knee injury

Abstract

In a rabbit model of knee injury, intra-articular injection of HA decreased adhesion formation and collagen content and increased ROM after prolonged immobilization. These results indicate that HA may be clinically useful to prevent adhesions and improve joint mobility in patients who require joint immobilization for up to 8 weeks.