Lactic Acidosis during Metformin Treatment in an Elderly Diabetic Patient with Impaired Renal Function

Abstract

In recent years, lactic acidosis has been described in association with metformin therapy in diabetics. We report a fatal case in an elderly diabetic patient with impaired renal function and cardiac insufficiency. The patient presented with an elevated plasma metformin concentration and a concomitant digitoxin intoxication.