Comparison of sensitivity for single-source and dual-interfering-source configurations in optical diffusion imaging

Abstract

A numerical study of single-source and dual-interfering-source modalities for optical imaging through biological media with a view to practical implications is given. Our comparisons are based on multigrid finite-difference frequency-domain solutions of the diffusion equation, for example, inhomogeneous imaging problems. Detector noise levels, the influence of boundaries, and ease of measurement are considered. This investigation indicates that a dual source, or dual-source data synthesized from single-source measurements, offers significant imaging opportunities when compared with single-source data.