Concepedia

Publication | Closed Access

CYP2C19 genotype affects diazepam pharmacokinetics and emergence from general anesthesia

DOI

83

Citations

27

References

2005

Year

Shinichi Inomata, Atsushi Nagashima, Fumio Itagaki, Masato Homma, Masuhiro Nishimura, Yoshiko Osaka, Kazuhiko Okuyama, Einosuke Tanaka, Takako Nakamura, Yukinao Kohda
Clinical Pharmacology & Therapeutics

Abstract

We found that the CYP2C19 genotype affects diazepam pharmacokinetics and emergence from general anesthesia and that the slow-emergence group possesses lower levels of CYP3A4 mRNA than are found in the rapid-emergence group.

References

YearCitations

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