Sublingual immunotherapy in children modulates allergen‐induced <i>in vitro</i> expression of cytokine mRNA in PBMC

Abstract

Sublingual immunotherapy induced a dose-dependent systemic allergen-specific immunological response in children with AR. During high-dose SLIT, there was activation of regulatory cytokine IL-10 and an inhibitory effect on IL-5 expression increase that was associated with TGF-beta.