In vivo uptake of lecithin-coated polystyrene beads by rat hepatocytes and sinusoidal endothelial cells

Abstract

Uptake of 240 nm lecithin-coated polystyrene beads was observed by Kupffer cells, endothelial cells and hepatocytes. These beads were considered to be transported across the endothelial cells by transcytosis. Pseudopodia and bristle-coated invaginations were not employed by the hepatocytes when incorporating the beads.