A multiplex model of combining gene‐based, protein‐based, and metabolite‐based with positive and negative markers in urine for the early diagnosis of prostate cancer

Abstract

Compared with single biomarker, the multiplex model including PCA3, TMPRSS2: ERG, Annexin A3 and Sarcosine adds even more to the diagnostic performance for predicting CaP. Further validation experiments and optimization for the strategy of constructing this model are warranted.