A highly sensitive cytotoxicity assay based on the release of reporter enzymes, from stably transfected cell lines

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.

Manfred Gossen, Heidelberg Bujard · Proceedings of the National Academy of Sciences · 1992 · 4.9K citations

Viral Replication, Molecular Regulation, Immunology +20

Firefly luciferase gene: structure and expression in mammalian cells.

Jeffrey R. de Wet, Keith V. Wood, M. DeLuca et al. · Molecular and Cellular Biology · 1987 · 3.1K citations · Full text

Firefly Luciferase, Genetics, Molecular Biology +16

Quantitative assay of the lytic action of immune lymphoid cells on 51-Cr-labelled allogeneic target cells in vitro; inhibition by isoantibody and by drugs.

K. T. Brunner, Jacques Mauël, J C Cerottini et al. · PubMed · 1968 · 1.4K citations · Full text

The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection.

C M Gorman, Glenn Merlino, Mark C. Willingham et al. · Proceedings of the National Academy of Sciences · 1982 · 1.4K citations · Full text

Viral Replication, Immunology, Molecular Biology +19

An enzyme-release assay for natural cytotoxicity

Carol Korzeniewski, Denis M. Callewaert · Journal of Immunological Methods · 1983 · 1.1K citations

Biochemistry, Medicine, Bioanalysis +6