Empiric recurrence risks in common and uncommon congenital heart lesions

Abstract

Abstract Empiric recurrence risks in sibs for the eight most common and four uncommon congenital heart lesions have been obtained from a study of 1405 patients with congenital cardiovascular malformations. Risks to offspring of parents with any of four common congenital heart diseases were determined in a study of 210 adults who had congenital heart defects and who had reproduced. The recurrence risks are presented and are found to approximate the prediction of the multifactorial inheritance hypothesis.