Concepedia

Docking, synthesis and pharmacological activity of novel urea-derivatives designed as p38 MAPK inhibitors

Raquel de Oliveira Lopes, Nelilma Correia Romeiro, Cleverton Kleiton Freitas de Lima, Leandro Louback da Silva, Ana Luísa P. Miranda, Paulo Gustavo Barboni Dantas Nascimento, Fernando Q. Cunha, Eliezer J. Barreiro, Lı́dia Moreira Lima

European Journal of Medicinal Chemistry · 2012 · 19 citations · 22 references

DOIFull text

Open access

Concepts

References

22

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Tim R. Mosmann · Journal of Immunological Methods · 1983 · 55.6K citations

, , +14

The Protein Data Bank

Helen M. Berman · Nucleic Acids Research · 2000 · 39.8K citations

, , +10

The PyMOL Molecular Graphics System

Warren L. DeLano · Medical Entomology and Zoology · 2002 · 18.1K citations

, , +11

Development and use of quantum mechanical molecular models. 76. AM1: a new general purpose quantum mechanical molecular model

Michael J. S. Dewar, Eve G. Zoebisch, Eamonn F. Healy et al. · Journal of the American Chemical Society · 1985 · 13.1K citations

, , +10

Improved protein–ligand docking using GOLD

Marcel L. Verdonk, Jason C. Cole, Michael J. Hartshorn et al. · Proteins Structure Function and Bioinformatics · 2003 · 3K citations · Full text

, , +17