Copper‐Catalyzed Di‐ and Trifluoromethylation of α,β‐Unsaturated Carboxylic Acids: A Protocol for Vinylic Fluoroalkylations

Abstract

Dual action: the Lewis acid CuF(2) ⋅2 H(2)O efficiently catalyzes the reaction between electrophilic fluoroalkylating agents and α,β-unsaturated carboxylic acids by dually activating both reactants, thus affording di- and trifluoromethyl alkenes in high yields with excellent E/Z selectivity.