Cloning of iNOS in the small spotted catshark (Scyliorhinus canicula)

Basic local alignment search tool

Stephen F. Altschul, Warren Gish, Webb Miller et al. · Journal of Molecular Biology · 1990 · 94.5K citations

Life Sciences, Bioinformatics, Sequence Analysis +3

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Julie Thompson, Desmond G. Higgins, Toby J. Gibson · Nucleic Acids Research · 1994 · 64.9K citations · Full text

Life Sciences, Bioinformatics, Sequence Analysis +14

A simple method for displaying the hydropathic character of a protein

Jack Kyte, Russell F. Doolittle · Journal of Molecular Biology · 1982 · 23.1K citations

Life Sciences, Biochemistry, Molecular Biology +12

Improved tools for biological sequence comparison.

William R. Pearson, David J. Lipman · Proceedings of the National Academy of Sciences · 1988 · 11.3K citations · Full text

Life Sciences, Bioinformatics, Biology +15

Tree View: An application to display phylogenetic trees on personal computers

Roderic Page · Computer applications in the biosciences · 1996 · 10.2K citations · Full text

Life Sciences, Biology, Visualization +17