A new 5-aminosalicylic acid multi-unit dosage form for the therapy of ulcerative colitis

Transit of pharmaceutical dosage forms through the small intestine.

S.S. Davis, John G. Hardy, J W Fara · Gut · 1986 · 848 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Swelling/deswelling of anionic copolymer gels

Atul Khare, Nikolaos A. Peppas · Biomaterials · 1995 · 425 citations

Natural Sciences, Materials Engineering, Materials Science +12

A pH-dependent colon targeted oral drug delivery system using methacrylic acid copolymers

M. Z. I. Khan, Željko Prebeg, Nevenka Kurjaković · Journal of Controlled Release · 1999 · 322 citations

Pharmacy, Pharmaceutics, Pharmacology +16

Gastrointestinal pH profiles in patients with inflammatory bowel disease

Press, Hauptmann, Hauptmann et al. · Alimentary Pharmacology & Therapeutics · 1998 · 244 citations

Medicine, Pharmacology, Pharmacotherapy +16

An in vitro investigation into the suitability of pH-dependent polymers for colonic targeting

Marianne Ashford, John T. Fell, David Attwood et al. · International Journal of Pharmaceutics · 1993 · 240 citations

Natural Sciences, Biomedical Engineering, Pharmaceutics +16