Electrochemical behavior of nitrofurantoin and assay of its formulations

Abstract

Abstract The electrochemical behavior of nitrofurantoin was studied by employing do polarography, cyclic voltammetry, and differential pulse polarography in universal buffers of pH 2.0–12.0. Kinetic parameters such as transfer coefficients, diffusion coefficients, and heterogeneous forward rate constant values were evaluated using these techniques. Differential pulse polarography was employed for the estimation of this drug in several pharmaceutical formulations.