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Phorbol ester (TPA) reduces prostaglandin E2-stimulated cAMP production by desensitization of prostaglandin E2 receptors in a clonal osteoblast-like cell line, MOB 3-4

SclerostinSignal TransductionMob 3-4Bone Morphogenic ProteinMedicineG Protein-coupled ReceptorPhysiologyReceptor (Biochemistry)Prostaglandin E2 ReceptorsEndocrinologyPharmacologyCell BiologyCell SignalingCellular PhysiologyPhorbol Ester