Hydropropidine: A novel, cell-impermeant fluorogenic probe for detecting extracellular superoxide

Superoxide reacts with hydroethidine but forms a fluorescent product that is distinctly different from ethidium: potential implications in intracellular fluorescence detection of superoxide

Hongtao Zhao, Shasi V. Kalivendi, Hao Zhang et al. · Free Radical Biology and Medicine · 2003 · 792 citations

Natural Sciences, Biophysics, Cell Biology +16

Selective fluorescent imaging of superoxide <i>in vivo</i> using ethidium-based probes

Kristine M. Robinson, Michael Janes, Mariana Pehar et al. · Proceedings of the National Academy of Sciences · 2006 · 768 citations · Full text

Life Sciences, Biochemistry, Cell Biology +14

Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitations of fluorescence

Hongtao Zhao, Joy Joseph, Henry M. Fales et al. · Proceedings of the National Academy of Sciences · 2005 · 570 citations

Natural Sciences, Biochemistry, Chemistry +15

Detection of 2-hydroxyethidium in cellular systems: a unique marker product of superoxide and hydroethidine

Jacek Zielonka, Jeannette Vásquez‐Vivar, Balaraman Kalyanaraman · Nature Protocols · 2007 · 414 citations

Life Sciences, Cell Biology, Toxicology +14

Synthesis and biochemical applications of a solid cyclic nitrone spin trap: a relatively superior trap for detecting superoxide anions and glutathiyl radicals

Hongtao Zhao, Joy Joseph, Hao Zhang et al. · Free Radical Biology and Medicine · 2001 · 399 citations

Life Sciences, Biochemistry, Chemistry +10