Adsorption of proteins onto hydrophobic polymer surfaces: Adsorption isotherms and kinetics

Abstract

Abstract Adsorption of albumin, γ‐globulin, and fibrinogen from solution, under both static and flow conditions, onto several hydrophobic polymers was studied using internal reflection infrared spectroscopy. Isotherm curves experimentally found were consistant with Langmuir type adsorption. The rate and amount of protein adsorbed was found to be dependent upon both the nature of the polymer substrate and on the flow rate of the solution.