Oxycodone Pharmacokinetics and Pharmacodynamics in the Rat in the Presence of the P-Glycoprotein Inhibitor PSC833

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues.

F Thiébaut, T Tsuruo, Hironobu Hamada et al. · Proceedings of the National Academy of Sciences · 1987 · 2.8K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +9

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites.

Carlos Cordon‐Cardo, James P. O’Brien, D Casals et al. · Proceedings of the National Academy of Sciences · 1989 · 1.7K citations · Full text

Medicine, Oncology, Pharmacology +16

OATP and P-Glycoprotein Transporters Mediate the Cellular Uptake and Excretion of Fexofenadine

Mirjana Cvetković, Brenda F. Leake, Martin F. Fromm et al. · Drug Metabolism and Disposition · 1999 · 595 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Increased drug delivery to the brain by P-glycoprotein inhibition

Abu Sadeque · Clinical Pharmacology & Therapeutics · 2000 · 423 citations

Medicine, Pharmacokinetics, Pharmacology +13

Transport of paclitaxel (Taxol) across the blood-brain barrier in vitro and in vivo

Stephan Fellner, Björn Bauer, David S. Miller et al. · Journal of Clinical Investigation · 2002 · 360 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17