Concepedia

The role of the anaesthetised guinea-pig in the preclinical cardiac safety evaluation of drug candidate compounds

Louise Marks, Samantha Borland, Karen Philp, Lorna Ewart, Pierre Lainée, Matthew Skinner, Sarah Kirk, Jean‐Pierre Valentin

Toxicology and Applied Pharmacology · 2012 · 36 citations · 45 references

DOI

Concepts

References

45

Small Sample Inference for Fixed Effects from Restricted Maximum Likelihood

Michael G. Kenward, James Roger · Biometrics · 1997 · 4.5K citations

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Hemodynamic determinants of the maximal rate of rise of left ventricular pressure

Andrew G. Wallace, N. Sheldon Skinner, Jere H. Mitchell · American Journal of Physiology-Legacy Content · 1963 · 322 citations

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IonWorks™ HT: A New High-Throughput Electrophysiology Measurement Platform

Kirk S. Schroeder, Brad Neagle, Derek J. Trezise et al. · SLAS DISCOVERY · 2003 · 222 citations · Full text

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Management of cardiac health in trastuzumab-treated patients with breast cancer: updated United Kingdom National Cancer Research Institute recommendations for monitoring

Anna Jones, Malcolm Barlow, Peter Barrett‐Lee et al. · British Journal of Cancer · 2009 · 216 citations · Full text

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On the relationship between block of the cardiac Na<sup>+</sup>channel and drug-induced prolongation of the QRS complex

AR Harmer, J-P Valentin, C E Pollard · British Journal of Pharmacology · 2011 · 159 citations · Full text

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