Concepedia

Real-time monitoring biomarker expression of carcinoma cells by surface plasmon resonance biosensors

Chang Liu, Tingjun Lei, Kosuke Ino, Tomokazu Matsue, Nongjian Tao, Chen-Zhong Li

Chemical Communications · 2012 · 59 citations · 16 references

DOI

Concepts

Abstract

A novel surface plasmon resonance (SPR) biosensor which is capable of monitoring proteomic biomarker secretion from living cells is reported here. Vascular endothelial growth factor (VEGF) secretion from living SKOV-3 ovarian cancer cells was measured for concept demonstration.

References

16

Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders.

Leonard G. Presta, H Chen, Shane J. O'Connor et al. · PubMed · 1997 · 1.6K citations

, , +17

Role of Vascular Endothelial Growth Factor in Ovarian Cancer

Sam Mesiano, Napoleone Ferrara, Robert B. Jaffe · American Journal Of Pathology · 1998 · 399 citations

, , +14

Cell Culture in 3-Dimensional Microfluidic Structure of PDMS (polydimethylsiloxane)

Éric Leclerc, Yasuyuki Sakai, Teruo Fujii · Biomedical Microdevices · 2003 · 321 citations

, , +14

Quantitative and simultaneous detection of four foodborne bacterial pathogens with a multi-channel SPR sensor

Allen D. Taylor, Jon J. Ladd, Qiuming Yu et al. · Biosensors and Bioelectronics · 2006 · 305 citations

, , +16

Detection of Protein Biomarkers Using RNA Aptamer Microarrays and Enzymatically Amplified Surface Plasmon Resonance Imaging

Yuan Li, Hye Jin Lee, Robert M. Corn · Analytical Chemistry · 2007 · 277 citations · Full text

, , +17