The Journal of Clinical Endocrinology & Metabolism · 1972 · 140 citations · 0 references
MedicineEndocrinologyObstetricsHormone BiochemistryReproductive EndocrinologySteroid BiochemistryGynecologic EndocrinologyMaternal-fetal PhysiologyPlacental PhysiologyPregnancyPregnancy EndocrinologyPregnancy PhysiologyBiochemical Pregnancy CorrelationEarly Pregnancy Hormonal DynamicsEstradiol LevelsEstradiol MeasurementFetal Weight EstimationPlacental Steroid TransferPregnancy-related Hormonal Changes
Estrone sulfate, estrone, estradiol and estriol were measured through the course of pregnancy in 85 women. Of the unconjugated estrogens, estradiol had the highest plasma concentration, being approximately twice that of estrone and four times that of estriol. Estrone sulfate level was twice that of estradiol. All estrogens measured showed the same pattern of increase with time. When plotted against fetal and placental weights, the increase in plasma concentration of all estrogens correlated better with fetal weight than with placental weight.