Significance of a Flat Small-intestinal Mucosa

Abstract

to this may cause less gastro-intestinal disturbance. The sideeffects of chlorphentermine S.A. may not, however, be entirely local in action, and it is possible that the anorectic action of chlorphentermine may be dependent on its function as a mild central emetic at medullary level. The 10 defaulters up to three months contained five on the test preparation and five on the placebo, so that it seems unlikely that the default rate was related to the gastro-intestinal effects of chlorphentermine. As a result of this investigation what conclusions can be drawn regarding chlorphentermine S.A ? It would appear to be of value as a supplement to the treatment of obesity, in which close medical supervision and encouragement of strict dietary measures are the mainstay of therapeutic management. By itself the drug has no definite role. It is recognized that the doctor often feels the need to prescribe an appetite suppres- sant for his obese patient who complains of excess appetite and requests a " slimming pill," and in such circumstances chlor- phentermine S.A. may be useful, since it is an anorectic but does not act as a cerebral stimulant.