Emerging infectious diseases · 2013 · 78 citations · 26 references
Virus EpidemiologyViral DiagnosticsSolid Organ TransplantationTransplantation MedicineHepatitis BUnited StatesAutoimmune Liver DiseaseCovid-19Hepatic DisordersViral HepatitisClinical EpidemiologyInfection ControlPublic HealthLaboratory MedicineDiagnostic VirologyInfectious Disease EpidemiologyInfectious Disease PreventionTransplantationHepatitis E VirusHepatitis E CasesVirologyDisease SurveillanceLiver TransplantationEpidemiologyHepatitis DHepatologyGlobal HealthInternational HealthHepatitisAcute Liver FailureLiver DiseaseMedicine
To investigate characteristics of hepatitis E cases in the United States, we tested samples from persons seronegative for acute hepatitis A and B whose clinical specimens were referred to the Centers for Disease Control and Prevention during June 2005-March 2012 for hepatitis E virus (HEV) testing. We found that 26 (17%) of 154 persons tested had hepatitis E. Of these, 15 had not recently traveled abroad (nontravelers), and 11 had (travelers). Compared with travelers, nontravelers were older (median 61 vs. 32 years of age) and more likely to be anicteric (53% vs. 8%); the nontraveler group also had fewer persons of South Asian ethnicity (7% vs. 73%) and more solid-organ transplant recipients (47% vs. 0). HEV genotype 3 was characterized from 8 nontravelers and genotypes 1 or 4 from 4 travelers. Clinicians should consider HEV infection in the differential diagnosis of hepatitis, regardless of patient travel history.
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R. P. Singh, Jolanta Kurz, Gilles Boiteau · Journal of Virological Methods · 1996 · 2.6K citations
Surveillance for waterborne-disease outbreaks--United States, 1993-1994.
Michael H. Kramer, Barbara L. Herwaldt, Gunther F. Craun et al. · PubMed · 1996 · 2.1K citations