Evaluation of the antitumour activity of the non-steroidal antioestrogen monohydroxytamoxifen in the DMBA-induced rat mammary carcinoma model

Mammary Cancer Induced by a Single Feeding of Polynuclear Hydrocarbons, and its Suppression

Charles Huggins, LORRAINE C. GRAND, Filomena P. Brillantes · Nature · 1961 · 786 citations

Medicine, Oncology, Toxicology +14

A MONOHYDROXYLATED METABOLITE OF TAMOXIFEN WITH POTENT ANTIOESTROGENIC ACTIVITY

V. Craig Jordan, Margaret Collins, Linda Rowsby et al. · Journal of Endocrinology · 1977 · 503 citations

Life Sciences, Endocrinology, Pharmacology +15

Estrogen Control of Progesterone Receptor in Human Breast Cancer: Role of Estradiol and Antiestrogen*

Kathryn B. Horwitz, Yoshihiro Koseki, William McGuire · Endocrinology · 1978 · 414 citations

Medicine, Endocrinology, Oncology +14

Effect of tamoxifen (ICI 46,474) on initiation and growth of DMBA-induced rat mammary carcinomata

V. Craig Jordan · European Journal of Cancer (1965) · 1976 · 372 citations

Medicine, Oncology, Pharmacology +14

The Metabolism of Tamoxifen (I.C.I. 46,474) Part I : In Laboratory Animals

J. M. Fromson, Stuart Pearson, Sara Bramah · Xenobiotica · 1973 · 178 citations

Medicine, Pharmacokinetics, Pharmacology +12