Ethyl pyruvate and ethyl lactate down-regulate the production of pro-inflammatory cytokines and modulate expression of immune receptors

On Respiratory Impairment in Cancer Cells

Otto Warbürg · Science · 1956 · 3.2K citations

Medicine, Cancer Biology, Oncology +13

Tumor-derived lactic acid modulates dendritic cell activation and antigen expression

Eva Gottfried, Leoni A. Kunz‐Schughart, Stephanie R. Ebner et al. · Blood · 2005 · 698 citations · Full text

Life Sciences, Immunology, Oncology +16

Binding and modification of proteins by methylglyoxal under physiological conditions. A kinetic and mechanistic study with N alpha-acetylarginine, N alpha-acetylcysteine, and N alpha-acetyllysine, and bovine serum albumin.

Theodore W. C. Lo, Marie Westwood, Antony C. McLellan et al. · Journal of Biological Chemistry · 1994 · 695 citations · Full text

Life Sciences, Biochemistry, Enzymology +11

Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation

Luis Ulloa, Mahendar Ochani, Huan Yang et al. · Proceedings of the National Academy of Sciences · 2002 · 592 citations · Full text

Veterinary Medicine, Immunology, Pharmacology +17

Distinct effects of glutathione disulphide on the nuclear transcription factors κB and the activator protein‐1

Dagmar Galter, Sabine Mihm, Wulf Dröge · European Journal of Biochemistry · 1994 · 273 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14