Concepedia

Sustained Activation of Fibroblast Transforming Growth Factor-β/Smad Signaling in a Murine Model of Scleroderma

Shinsuke Takagawa, Gabriella Lakos, Yasuji Mori, John Varga, Toshiyuki Yamamoto, Kiyoshi Nishioka

Journal of Investigative Dermatology · 2003 · 123 citations · 62 references

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62

Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling

Atsuhito Nakao, Mozhgan Afrakhte, Anita Morn et al. · Nature · 1997 · 1.8K citations

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Direct binding of Smad3 and Smad4 to critical TGFβ‐inducible elements in the promoter of human plasminogen activator inhibitor‐type 1 gene

Sylviane Dennler · The EMBO Journal · 1998 · 1.8K citations · Full text

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The MAD-Related Protein Smad7 Associates with the TGFβ Receptor and Functions as an Antagonist of TGFβ Signaling

Hidetoshi Hayashi, Shirin Abdollah, Yubin Qiu et al. · Cell · 1997 · 1.3K citations · Full text

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Smad7 Binds to Smurf2 to Form an E3 Ubiquitin Ligase that Targets the TGFβ Receptor for Degradation

Peter A. Kavsak, Richele K. Rasmussen, Carrie G. Causing et al. · Molecular Cell · 2000 · 1.3K citations · Full text

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Smurf1 Interacts with Transforming Growth Factor-β Type I Receptor through Smad7 and Induces Receptor Degradation

Takanori Ebisawa, Minoru Fukuchi, Gyo Murakami et al. · Journal of Biological Chemistry · 2001 · 841 citations · Full text

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