Evidence for an interferon-related inflammatory reaction in the trisomy 16 mouse brain leading to caspase-1-mediated neuronal apoptosis

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry · 1985 · 21.7K citations · Full text

Natural Sciences, Biochemistry, Chemistry +17

A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes

Nancy A. Thornberry, Herbert G. Bull, Jimmy Calaycay et al. · Nature · 1992 · 2.6K citations

Life Sciences, Immunology, Molecular Biology +12

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme

Cell · 1993 · 2.5K citations · Full text

Life Sciences, Genetics, Molecular Biology +10

Optimized survival of hippocampal neurons in B27‐supplemented neurobasal™, a new serum‐free medium combination

Gregory J. Brewer, John R. Torricelli, E. K. Evege et al. · Journal of Neuroscience Research · 1993 · 2.3K citations

Life Sciences, Neurobiology, Neuroscience +11

Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease.

W. Sue T. Griffin, Laura Stanley, Lon R. White et al. · Proceedings of the National Academy of Sciences · 1989 · 1.8K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17