Glibenclamide-Induced Apoptosis Is Specifically Enhanced by Expression of the Sulfonylurea Receptor Isoform SUR1 but Not by Expression of SUR2B or the Mutant SUR1(M1289T)

Glucose and Tolbutamide Induce Apoptosis in Pancreatic β-Cells

Ioulia B Efanova, Boris Zhivotovsky, Martin Köhler et al. · Journal of Biological Chemistry · 1998 · 366 citations · Full text

Life Sciences, Cell Biology, Pharmacology +16

Sulfonylurea Induced β-Cell Apoptosis in Cultured Human Islets

Kathrin Maedler, Richard D. Carr, Domenico Bosco et al. · The Journal of Clinical Endocrinology & Metabolism · 2005 · 334 citations · Full text

Medicine, Endocrinology, Pharmacology +15

SUR1 Regulates PKA-independent cAMP-induced Granule Priming in Mouse Pancreatic B-cells

Lena Eliasson, Xiaosong Ma, Erik Renström et al. · The Journal of General Physiology · 2003 · 263 citations · Full text

Life Sciences, Endocrinology, Physiology +17

Potassium channel openers require ATP to bind to and act through sulfonylurea receptors

Mathias Schwanstecher · The EMBO Journal · 1998 · 218 citations · Full text

Natural Sciences, Biochemistry, Pharmacology +14

Glucose- and Interleukin-1β-Induced β-Cell Apoptosis Requires Ca2+ Influx and Extracellular Signal-Regulated Kinase (ERK) 1/2 Activation and Is Prevented by a Sulfonylurea Receptor 1/Inwardly Rectifying K+ Channel 6.2 (SUR/Kir6.2) Selective Potassium Channel Opener in Human Islets

Kathrin Maedler, Joachim Størling, Jeppe Sturis et al. · Diabetes · 2004 · 145 citations

Life Sciences, Endocrinology, Physiology +17