Concepedia

UV-Induced TA Photoproducts: Formation and Hydrolysis in Double-Stranded DNA

Saâdia Asgatay, Agathe Martinez, Stéphanie Castex, Dominique Harakat, Coralie Philippe, Thierry Douki, Pascale Clivio

Journal of the American Chemical Society · 2010 · 20 citations · 18 references

DOI

Concepts

Abstract

Hydrolysis of TA photoproduct leads to two derivatives presenting different formation kinetic profiles depending on the oligomer content. The formation efficiency of TA photoproducts in UV-C-irradiated DNA slightly exceeds the formation of the trans,syn cyclobutane pyrimidine dimer at TT sites.

References

18

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Individual Determination of the Yield of the Main UV-Induced Dimeric Pyrimidine Photoproducts in DNA Suggests a High Mutagenicity of CC Photolesions

Thierry Douki, Jean Cadet · Biochemistry · 2001 · 326 citations

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Thierry Douki, Magali Court, Sylvie Sauvaigo et al. · Journal of Biological Chemistry · 2000 · 244 citations · Full text

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Respective roles of cyclobutane pyrimidine dimers, (6-4)photoproducts, and minor photoproducts in ultraviolet mutagenesis of repair-deficient xeroderma pigmentosum A cells.

Eriko Otoshi, Takashi Yagi, Toshio Mori et al. · PubMed · 2000 · 68 citations

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