Hepatitis C virus (HCV) NS5A protein: role in HCV replication and resistance to interferon‐<b>α</b>

Abstract

The hepatitis C virus (HCV) non-structural (NS) 5A protein appears to play an important regulatory role on viral replication and could also be involved in viral pathogenesis. HCV resistance to interferon is a complex mechanism involving multiple causes, among which certain NS5A functions could play a role.