Concepedia

Cationic Oligo(p‐phenylene vinylene) Materials for Combating Drug Resistance of Cancer Cells by Light Manipulation

Bing Wang, Huanxiang Yuan, Zhang Liu, Chenyao Nie, Libing Liu, Fengting Lv, Yilin Wang, Shu Wang

Advanced Materials · 2014 · 48 citations · 23 references

DOI

Concepts

Abstract

An unconventional strategy that can be temporally and remotely activated with light to combat the drug resistance of cancer cells is developed. A cell-membrane-anchored photosensitizer (OPV) is used to enhance anticancer drug uptake and restore toxicity in resistant cancer cells. This method recovers the activity of the already established anticancer drugs, and provides a new strategy for the development of light manipulation to combat anticancer resistance.

References

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