FIT probes: Peptide nucleic acid probes with a fluorescent base surrogate enable real-time DNA quantification and single nucleotide polymorphism discovery

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

John R. Riordan, Johanna M. Rommens, Bat-Sheva Kerem et al. · Science · 1989 · 7.4K citations

Life Sciences, Genetics, Molecular Genetics +12

Molecular Beacons: Probes that Fluoresce upon Hybridization

Sanjay Tyagi, Fred Russell Kramer · Nature Biotechnology · 1996 · 4.2K citations

Natural Sciences, Biology, Molecular Biology +9

Identification of the Cystic Fibrosis Gene: Genetic Analysis

Bat-Sheva Kerem, Johanna M. Rommens, Janet A. Buchanan et al. · Science · 1989 · 4.1K citations

Life Sciences, Genetics, Molecular Genetics +10

Identification of the Cystic Fibrosis Gene: Chromosome Walking and Jumping

Johanna M. Rommens, Michael C. Iannuzzi, Bat-Sheva Kerem et al. · Science · 1989 · 3.2K citations

Life Sciences, Genetics, Molecular Genetics +11

Detection of specific polymerase chain reaction product by utilizing the 5'----3' exonuclease activity of Thermus aquaticus DNA polymerase.

Pamela M. Holland, Richard D. Abramson, R. R. Watson et al. · Proceedings of the National Academy of Sciences · 1991 · 2.7K citations

Life Sciences, Biotechnology, Molecular Biology +15