Synthesis of pentaarabinofuranosyl structure motif A of Mycobacterium tuberculosis

Abstract

The first synthesis of motif A, the branched chain arabinofuranosyl pentasaccharide [t-β-Araf-(1 → 2)-α-D-Araf]2-3,5-α-D-Araf-(1 → 5) which constitutes the major humoral immunological epitope in the arabinogalactan cell wall of Mycobacterium tuberculosis is described.