Bioscience Biotechnology and Biochemistry · 2010 · 44 citations · 6 references
Life SciencesMicrobiologyMolecular BiologyGene ExpressionMicrobial GeneticsTranscriptional RegulationBacterial Gene RegulationGene Regulation In MicrobesMicrobial Gene Regulatory NetworksQuorum SensingTranscriptional Regulation In ProkaryotesVirulence Gene RegulationEscherichia ColiQuorum Sensing Control Of OperonsQuorum Sensing Gene RegulationQuorum Sensing GenesQuorum Sensing RegulationQuorum Sensing RegulatorsQuorum Sensing SignalingQuorum Sensing Signals
Chromobacterium violaceum produces the purple pigment violacein by quorum-sensing regulation. 20-bp of the lux box-like sequence was found upstream of vioA in C. violaceum ATCC 12472. CviR received C10-HSL and C6-HSL and activated the transcription of vioA in Escherichia coli. However, in strain ATCC 12472, C6-HSL inhibited both C10-HSL-mediated violacein production and the transcription of vioA.
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