Concepedia

The Effect of Creatine and Coenzyme Q10 Combination Therapy on Mild Cognitive Impairment in Parkinson's Disease

Zhenguang Li, Pengfei Wang, Zhancai Yu, Yannan Cong, Hairong Sun, Jiangshan Zhang, Jinbiao Zhang, Chao Sun, Yong Zhang, Xiaohua Ju

European Neurology · 2015 · 73 citations · 23 references

DOI

Abstract

Combination therapy with creatine and CoQ10 could delay the decline of cognitive function in PD-MCI patients and could lower their plasma PL levels; therefore, this combination therapy may have a neuroprotective function.

References

23

The Montreal Cognitive Assessment, MoCA: A Brief Screening Tool For Mild Cognitive Impairment

Ziad Nasreddine, Natalie A. Phillips, Valérie Bédirian et al. · Journal of the American Geriatrics Society · 2005 · 24.2K citations

Effects of Coenzyme Q10 in Early Parkinson Disease

Clifford W. Shults · Archives of Neurology · 2002 · 967 citations

A double‐blind, placebo‐controlled study to assess the mitochondria‐targeted antioxidant MitoQ as a disease‐modifying therapy in Parkinson's disease

Barry Snow, Fiona L. Rolfe, Michelle Lockhart et al. · Movement Disorders · 2010 · 588 citations

, , +15

A randomized, double-blind, futility clinical trial of creatine and minocycline in early Parkinson disease

Neurology · 2006 · 442 citations

A Randomized Clinical Trial of High-Dosage Coenzyme Q10 in Early Parkinson Disease

JAMA Neurology · 2014 · 381 citations · Full text