Copper-catalyzed oxidative cascade coupling of N-alkyl-N-phenylacrylamides with aryl aldehydes

Abstract

An oxidative cascade coupling reaction between <italic>N</italic>-alkyl-<italic>N</italic>-phenylacrylamides and aryl aldehydes using CuCl₂/TBHP (<italic>tert</italic>-butyl hydroperoxide) as a catalyst and oxidant was developed.