Concepedia

<i>TMPRSS2</i> : <i>ERG</i> Fusion Identifies a Subgroup of Prostate Cancers with a Favorable Prognosis

Outi R. Saramäki, Anna E. Harjula, Paula Martikainen, Robert L. Vessella, Teuvo L.J. Tammela, Tapio Visakorpi

Clinical Cancer Research · 2008 · 246 citations · 25 references

DOI

Abstract

The TMPRSS2:ERG rearrangement can be found in about one third of prostate cancers. A subgroup of prostate cancer patients with a good prognosis may be identified by the rearrangement.

References

25

Recurrent Fusion of <i>TMPRSS2</i> and ETS Transcription Factor Genes in Prostate Cancer

Scott A. Tomlins, Daniel R. Rhodes, Sven Perner et al. · Science · 2005 · 3.8K citations

, , +19

Amplification and overexpression of androgen receptor gene in hormone-refractory prostate cancer.

Marika J. Linja, Kimmo Savinainen, Outi R. Saramäki et al. · PubMed · 2001 · 768 citations

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TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort

Francesca Demichelis, Katja Fall, Sven Perner et al. · Oncogene · 2007 · 648 citations

, , +9

Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2.

Biaoyang Lin, Camari Ferguson, James T. White et al. · PubMed · 1999 · 543 citations

, , +13

<i>TMPRSS2:ERG</i> Fusion-Associated Deletions Provide Insight into the Heterogeneity of Prostate Cancer

Sven Perner, Francesca Demichelis, Rameen Beroukhim et al. · Cancer Research · 2006 · 500 citations · Full text