Freezing of Whole Blood

Abstract

It-is possible to use radioiron as an indicator of altered hematopoiesis, as shown in Fig. 2. Suspensions of marrow from patients with untreated pernicious anemia have repeatedly shown an acceleration of the rate of iron uptake after the addition of liver or folic acid as compared with control studies. This has not occurred in conditions other than those characterized by specific deficiencies of the substances used. These observations on the marrow cells in untreated pernicious anemia indicate that these effective therapeutic agents act directly on the immature erythrocytes.