Indian Journal of Pharmacology · 2011 · 17 citations · 11 references
Life SciencesMicrobiologyPharmacologyAntimicrobial PharmacologyAntimicrobial ResistancePlant-microbe InteractionsAntibacterial AgentsAntibacterial PharmacologyAntibacterial ResistanceAntibiotic ResistanceResistance In Gram-negative BacteriaResistance In Gram-positive BacteriaAminoglycoside AntibioticsAminoglycoside Resistance MechanismsAntimicrobial Natural ProductsEscherichia ColiNovel Antibacterial AgentsResistance Mechanisms In Gram-negative BacteriaResistance Mechanisms In Gram-positive BacteriaSynergistic Impacts
OBJECTIVE: In this work, we report the antibacterial and modulatory activity of Lantana montevidensis Briq. MATERIALS AND METHODS: The antibacterial activities of leaf (LELm) and root (RELm) extracts alone or in association with aminoglycosides were determined by a microdilution test. Multiresistant strains of Escherichia coli (Ec 27) and Staphylococcus aureus (Sa 358) were used. RESULTS: The results show the inhibitory activity of LELm against E. coli (minimal inhibitory concentration [MIC] 16 μg/mL) and S. aureus (MIC 128 μg/mL). The synergistic effect of the extracts and aminoglycosides was verified too. The maximum effects were obtained with RELm with gentamicin against E. coli with MIC reduction (312 to 2 μL). CONCLUSION: The data from this study are indicative of the activity antibacterial of extracts of L. montevidensis and its potential in modifying the resistance of aminoglycosides.
11
Ravinder Kumar Kohli, Daizy R. Batish, Harminder Pal Singh et al. · Biological Invasions · 2006 · 331 citations
Tsuneatsu Nagao, Fumiko Abe, Junei Kinjo et al. · Biological and Pharmaceutical Bulletin · 2002 · 175 citations · Full text
Henrique Douglas Melo Coutinho, José Galberto Martins da Costa, José P. Siqueira-Júnior et al. · Revista Brasileira de Farmacognosia · 2008 · 137 citations · Full text