A new approach to treatment of bleeding episodes in young hemophilia patients: a single bolus megadose of recombinant activated factor VII (NovoSeven®)

Home Treatment of Mild to Moderate Bleeding Episodes Using Recombinant Factor VIIa (Novoseven) in Haemophiliacs with Inhibitors

Louis M. Aledort, Diana S. Beardsley, Herbert Cooper et al. · Thrombosis and Haemostasis · 1998 · 355 citations

Medicine, Pharmacology, Pharmacotherapy +15

The Treatment of Bleeding in Acquired Haemophilia with Recombinant Factor VIIa: A Multicentre Study

C. R. M. Hay, Claude Négrier, C A Ludlam · Thrombosis and Haemostasis · 1997 · 350 citations

Medicine, Hematology, Pharmacotherapy +13

The effect of fibrin structure on fibrinolysis.

Don A. Gabriel, Kathleen M. Muga, Emily Boothroyd · Journal of Biological Chemistry · 1992 · 267 citations · Full text

Life Sciences, Biochemistry, Physiology +16

Fibrin in human plasma: Gel architectures governed by rate and nature of fibrinogen activation

Birger Blombäck, Kjell Carlsson, Kamaran Fatah et al. · Thrombosis Research · 1994 · 260 citations

Life Sciences, Biochemistry, Biophysics +16

Activated factor VII activates factors IX and X on the surface of activated platelets: thoughts on the mechanism of action of high-dose activated factor VII.

Maureane Hoffman, Dougald M. Monroe, H R Roberts · PubMed · 1998 · 245 citations

Medicine, Hematology, Pharmacology +17