NK/T-cell Lymphoma in a Child With Hypersensitivity to Mosquito Bites

Abstract

Hypersensitivity to mosquito bite (HMB) is defined as intense skin reactive lesion after mosquito bite. However, some kind of malignant tumor is closely associated with HMB, especially natural killer (NK)/T-cell lymphoma. We described a nasal-type NK/T-cell lymphoma in a 9-year-old girl after a history of 2 years earlier of HMB. Pathologic evaluation revealed the typical histologic features of NK/T-cell lymphoma, and the dermal and subcutaneous inflammatory reaction of HMB lesions. HMB is rarely reported and should be kept in mind as a clinical sign of subsequent NK/T-cell lymphoma in Asian country where HMB is relatively frequently encountered.